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Mrgprd(Cre) lineage neurons mediate optogenetic allodynia through an emergent polysynaptic circuit

Most cutaneous C fibers, including both peptidergic and nonpeptidergic subtypes, are presumed to be nociceptors and respond to noxious input in a graded manner. However, mechanically sensitive, nonpeptidergic C fibers also respond to mechanical input in the innocuous range, so the degree to which th...

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Detalles Bibliográficos
Autores principales: Warwick, Charles, Cassidy, Colleen, Hachisuka, Junichi, Wright, Margaret C., Baumbauer, Kyle M., Adelman, Peter C., Lee, Kuan H., Smith, Kelly M., Sheahan, Tayler D., Ross, Sarah E., Koerber, H. Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206522/
https://www.ncbi.nlm.nih.gov/pubmed/34130311
http://dx.doi.org/10.1097/j.pain.0000000000002227