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Targeted Expression of Myelin Autoantigen in the Periphery Induces Antigen-Specific T and B Cell Tolerance and Ameliorates Autoimmune Disease

There is a great interest in developing antigen-specific therapeutic approaches for the treatment of autoimmune diseases without compromising normal immune function. The key challenges are to control all antigen-specific lymphocyte populations that contribute to pathogenic inflammatory processes and...

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Detalles Bibliográficos
Autores principales: Na, Shin-Young, Krishnamoorthy, Gurumoorthy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206569/
https://www.ncbi.nlm.nih.gov/pubmed/34149706
http://dx.doi.org/10.3389/fimmu.2021.668487