Loss of Wiz Function Affects Methylation Pattern in Palate Development and Leads to Cleft Palate

WIZ (Widely Interspaced Zinc Finger) is associated with the G9a-GLP protein complex, a key H3K9 methyltransferase suggesting a role in transcriptional repression. However, its role in embryonic development is poorly described. In order to assess the loss of function of WIZ, we generated CRISPR/Cas9...

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Detalles Bibliográficos
Autores principales: Bukova, Ivana, Szczerkowska, Katarzyna Izabela, Prochazkova, Michaela, Beck, Inken M., Prochazka, Jan, Sedlacek, Radislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206640/
https://www.ncbi.nlm.nih.gov/pubmed/34150743
http://dx.doi.org/10.3389/fcell.2021.620692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206640/
https://www.ncbi.nlm.nih.gov/pubmed/34150743
http://dx.doi.org/10.3389/fcell.2021.620692

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