Cargando…
Loss of Wiz Function Affects Methylation Pattern in Palate Development and Leads to Cleft Palate
WIZ (Widely Interspaced Zinc Finger) is associated with the G9a-GLP protein complex, a key H3K9 methyltransferase suggesting a role in transcriptional repression. However, its role in embryonic development is poorly described. In order to assess the loss of function of WIZ, we generated CRISPR/Cas9...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206640/ https://www.ncbi.nlm.nih.gov/pubmed/34150743 http://dx.doi.org/10.3389/fcell.2021.620692 |