Disruption of disulfides within RBD of SARS‐CoV‐2 spike protein prevents fusion and represents a target for viral entry inhibition by registered drugs

The SARS‐CoV‐2 pandemic imposed a large burden on health and society. Therapeutics targeting different components and processes of the viral infection replication cycle are being investigated, particularly to repurpose already approved drugs. Spike protein is an important target for both vaccines an...

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Detalles Bibliográficos
Autores principales: Manček‐Keber, Mateja, Hafner‐Bratkovič, Iva, Lainšček, Duško, Benčina, Mojca, Govednik, Tea, Orehek, Sara, Plaper, Tjaša, Jazbec, Vid, Bergant, Valter, Grass, Vincent, Pichlmair, Andreas, Jerala, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206760/
https://www.ncbi.nlm.nih.gov/pubmed/34004056
http://dx.doi.org/10.1096/fj.202100560R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206760/
https://www.ncbi.nlm.nih.gov/pubmed/34004056
http://dx.doi.org/10.1096/fj.202100560R

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