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Disruption of disulfides within RBD of SARS‐CoV‐2 spike protein prevents fusion and represents a target for viral entry inhibition by registered drugs
The SARS‐CoV‐2 pandemic imposed a large burden on health and society. Therapeutics targeting different components and processes of the viral infection replication cycle are being investigated, particularly to repurpose already approved drugs. Spike protein is an important target for both vaccines an...
Autores principales: | Manček‐Keber, Mateja, Hafner‐Bratkovič, Iva, Lainšček, Duško, Benčina, Mojca, Govednik, Tea, Orehek, Sara, Plaper, Tjaša, Jazbec, Vid, Bergant, Valter, Grass, Vincent, Pichlmair, Andreas, Jerala, Roman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206760/ https://www.ncbi.nlm.nih.gov/pubmed/34004056 http://dx.doi.org/10.1096/fj.202100560R |
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