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Sphingosine Kinase 1 Regulates the Pulmonary Vascular Immune Response

The aberrant proliferation of pulmonary artery smooth muscle (PASMCs) cells is a defining characteristic of pulmonary arterial hypertension (PAH) and leads to increased vascular resistance, elevated pulmonary pressure, and right heart failure. The sphingosine kinase 1 (SPHK1)/sphingosine-1 phosphate...

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Detalles Bibliográficos
Autores principales: Bai, Yang, Lockett, Angelia D., Gomes, Marta T., Stearman, Robert S., Machado, Roberto F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206894/
https://www.ncbi.nlm.nih.gov/pubmed/34133010
http://dx.doi.org/10.1007/s12013-021-01006-8