Decoupling Growth and Protein Production in CHO Cells: A Targeted Approach

Fed-batch cultures of Chinese Hamster Ovary cells have been used to produce high quantities of biotherapeutics, particularly monoclonal antibodies. However, a growing number of next-generation biotherapeutics, such as bi-specific antibodies and fusion proteins, are difficult to express using standar...

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Detalles Bibliográficos
Autores principales: Donaldson, James S., Dale, Matthew P., Rosser, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207133/
https://www.ncbi.nlm.nih.gov/pubmed/34150726
http://dx.doi.org/10.3389/fbioe.2021.658325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207133/
https://www.ncbi.nlm.nih.gov/pubmed/34150726
http://dx.doi.org/10.3389/fbioe.2021.658325

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