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A Systems-Based Key Innovation-Driven Approach Infers Co-option of Jaw Developmental Programs During Cancer Progression

Cancer acquires metastatic potential and evolves via co-opting gene regulatory networks (GRN) of embryonic development and tissue homeostasis. Such GRNs are encoded in the genome and frequently conserved among species. Considering that all metazoa have evolved from a common ancestor via major macroe...

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Detalles Bibliográficos
Autores principales: Marquardt, Stephan, Pavlopoulou, Athanasia, Takan, Işıl, Dhar, Prabir, Pützer, Brigitte M., Logotheti, Stella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207138/
https://www.ncbi.nlm.nih.gov/pubmed/34150777
http://dx.doi.org/10.3389/fcell.2021.682619