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Multiscale Simulations on the Catalytic Plasticity of CYP76AH1

The catalytic promiscuity and fidelity of cytochrome P450 enzymes are widespread in the skeletal modification of terpenoid natural products and have attracted much attention. CYP76AH1 is involved in key modification reactions in the biosynthetic pathway of tanshinone, a well-known medicinal norditer...

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Detalles Bibliográficos
Autores principales: Qiu, Yufan, Diao, Hongjuan, Zheng, Ying, Wu, Ruibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207200/
https://www.ncbi.nlm.nih.gov/pubmed/34150721
http://dx.doi.org/10.3389/fchem.2021.689731