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Enhanced recombinant expression and purification of human IRAP for biochemical and crystallography studies

Insulin-regulated aminopeptidase (IRAP) in humans is a membrane bound enzyme that has multiple functions. It was first described as a companion protein of the insulin-responsive glucose transporter, Glut4, in specialized vesicles. The protein has subsequently been shown to be identical to the oxytoc...

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Detalles Bibliográficos
Autores principales: Sui, Lufei, Guo, Hwai-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207215/
https://www.ncbi.nlm.nih.gov/pubmed/34169156
http://dx.doi.org/10.1016/j.bbrep.2021.101042