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Altered APE1 activity on abasic ribonucleotides is mediated by changes in the nucleoside sugar pucker
Ribonucleotides (rNTPs) are predicted to be incorporated into the genome at a rate of up to 3 million times per cell division, making rNTPs the most common non-standard nucleotide in the human genome. Typically, misinserted ribonucleotides are repaired by the ribonucleotide excision repair (RER) pat...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207216/ https://www.ncbi.nlm.nih.gov/pubmed/34188778 http://dx.doi.org/10.1016/j.csbj.2021.05.035 |