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A novel single-domain antibody multimer that potently neutralizes tetanus neurotoxin

Tetanus antitoxin, produced in animals, has been used for the prevention and treatment of tetanus for more than 100 years. The availability of antitoxins, ethical issues around production, and risks involved in the use of animal derived serum products are a concern. We therefore developed a llama de...

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Detalles Bibliográficos
Autores principales: de Smit, Hans, Ackerschott, Bart, Tierney, Robert, Stickings, Paul, Harmsen, Michiel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207222/
https://www.ncbi.nlm.nih.gov/pubmed/34169269
http://dx.doi.org/10.1016/j.jvacx.2021.100099