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Melatonin Protects Against Ischemic Brain Injury by Modulating PI3K/AKT Signaling Pathway via Suppression of PTEN Activity

Stroke is one of the leading causes of death and disability worldwide with limited therapeutic options. Melatonin can attenuate ischemic brain damage with improved functional outcomes. However, the cellular mechanisms of melatonin-driven neuroprotection against post-stroke neuronal death remain unkn...

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Detalles Bibliográficos
Autores principales: Ran, Yuanyuan, Ye, Lin, Ding, Zitong, Gao, Fuhai, Yang, Shuiqing, Fang, Boyan, Liu, Zongjian, Xi, Jianing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207287/
https://www.ncbi.nlm.nih.gov/pubmed/34120482
http://dx.doi.org/10.1177/17590914211022888