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A method for cryopreservation and single nucleus RNA-sequencing of normal adult human interventricular septum heart tissue reveals cellular diversity and function

BACKGROUND: Single cell sequencing of human heart tissue is technically challenging and methods to cryopreserve heart tissue for obtaining single cell information have not been standardized. Studies published to date have used varying methods to preserve and process human heart tissue, and have gene...

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Detalles Bibliográficos
Autores principales: Larson, Amy, Chin, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207585/
https://www.ncbi.nlm.nih.gov/pubmed/34130702
http://dx.doi.org/10.1186/s12920-021-01011-z