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SMAD1 as a biomarker and potential therapeutic target in drug-resistant multiple myeloma

BACKGROUND: SMAD1, a central mediator in TGF-β signaling, is involved in a broad range of biological activities including cell growth, apoptosis, development and immune response, and is implicated in diverse type of malignancies. Whether SMAD1 plays an important role in multiple myeloma (MM) pathoge...

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Detalles Bibliográficos
Autores principales: Wu, Jian, Zhang, Min, Faruq, Omar, Zacksenhaus, Eldad, Chen, Wenming, Liu, Aijun, Chang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207655/
https://www.ncbi.nlm.nih.gov/pubmed/34134766
http://dx.doi.org/10.1186/s40364-021-00296-7