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Role of AmpG in the resistance to β-lactam agents, including cephalosporins and carbapenems: candidate for a novel antimicrobial target

BACKGROUND: A complex cascade of genes, enzymes, and transcription factors regulates AmpC β-lactamase overexpression. We investigated the network of AmpC β-lactamase overexpression in Klebsiella aerogenes and identified the role of AmpG in resistance to β-lactam agents, including cephalosporins and...

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Detalles Bibliográficos
Autores principales: D’Souza, Roshan, Nguyen, Le Phuong, Pinto, Naina A., Lee, Hyunsook, Vu, Thao Nguyen, Kim, Hoyoung, Cho, Hyun Soo, Yong, Dongeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207665/
https://www.ncbi.nlm.nih.gov/pubmed/34134705
http://dx.doi.org/10.1186/s12941-021-00446-7