Prospective prediction of clinical drug response in high-grade gliomas using an ex vivo 3D cell culture assay

BACKGROUND: Clinical outcomes in high-grade glioma (HGG) have remained relatively unchanged over the last 3 decades with only modest increases in overall survival. Despite the validation of biomarkers to classify treatment response, most newly diagnosed (ND) patients receive the same treatment regim...

Descripción completa

Detalles Bibliográficos
Autores principales: Shuford, Stephen, Lipinski, Lindsay, Abad, Ajay, Smith, Ashley M, Rayner, Melissa, O’Donnell, Lauren, Stuart, Jeremy, Mechtler, Laszlo L, Fabiano, Andrew J, Edenfield, Jeff, Kanos, Charles, Gardner, Stephen, Hodge, Philip, Lynn, Michael, Butowski, Nicholas A, Han, Seunggu J, Redjal, Navid, Crosswell, Howland E, Vibat, Cecile Rose T, Holmes, Lillia, Gevaert, Matthew, Fenstermaker, Robert A, DesRochers, Teresa M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207705/
https://www.ncbi.nlm.nih.gov/pubmed/34142085
http://dx.doi.org/10.1093/noajnl/vdab065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207705/
https://www.ncbi.nlm.nih.gov/pubmed/34142085
http://dx.doi.org/10.1093/noajnl/vdab065

Ejemplares similares