Cargando…

Identification of monoclonal antibodies against human renal glomerular endothelial cells in lupus nephritis that induce endothelial interferon-alpha production

BACKGROUND: The pathogenesis of lupus nephritis (LN) remains not fully understood. In this study, we aimed to explore the pathogenic roles of autoantibodies against human renal glomerular endothelial cells (HRGEC) in LN patients. METHODS: The serum levels of anti-HRGEC antibodies in systemic lupus e...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Ya-Chiao, Tsai, I-Jung, Hsu, Hui-Yao, Chiang, Bor-Luen, Yang, Yao-Hsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207712/
https://www.ncbi.nlm.nih.gov/pubmed/34134755
http://dx.doi.org/10.1186/s13075-021-02552-5