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Programmed suppression of oxidative phosphorylation and mitochondrial function by gestational alcohol exposure correlate with widespread increases in H3K9me2 that do not suppress transcription

BACKGROUND: A critical question emerging in the field of developmental toxicology is whether alterations in chromatin structure induced by toxicant exposure control patterns of gene expression or, instead, are structural changes that are part of a nuclear stress response. Previously, we used a mouse...

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Detalles Bibliográficos
Autores principales: Chang, Richard C., Thomas, Kara N., Mehta, Nicole A., Veazey, Kylee J., Parnell, Scott E., Golding, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207718/
https://www.ncbi.nlm.nih.gov/pubmed/34130715
http://dx.doi.org/10.1186/s13072-021-00403-w