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Programmed suppression of oxidative phosphorylation and mitochondrial function by gestational alcohol exposure correlate with widespread increases in H3K9me2 that do not suppress transcription
BACKGROUND: A critical question emerging in the field of developmental toxicology is whether alterations in chromatin structure induced by toxicant exposure control patterns of gene expression or, instead, are structural changes that are part of a nuclear stress response. Previously, we used a mouse...
Autores principales: | Chang, Richard C., Thomas, Kara N., Mehta, Nicole A., Veazey, Kylee J., Parnell, Scott E., Golding, Michael C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207718/ https://www.ncbi.nlm.nih.gov/pubmed/34130715 http://dx.doi.org/10.1186/s13072-021-00403-w |
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