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Cardioprotective effect of nicorandil on isoproterenol induced cardiomyopathy in the Mdx mouse model

BACKGROUND: Duchenne muscular dystrophy (DMD) associated cardiomyopathy is a major cause of morbidity and mortality. In an in vitro DMD cardiomyocyte model, nicorandil reversed stress-induced cell injury through multiple pathways implicated in DMD. We aimed to test the efficacy of nicorandil on the...

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Detalles Bibliográficos
Autores principales: Sullivan, Rachel T., Lam, Ngoc T., Haberman, Margaret, Beatka, Margaret J., Afzal, Muhammad Z., Lawlor, Michael W., Strande, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207777/
https://www.ncbi.nlm.nih.gov/pubmed/34130633
http://dx.doi.org/10.1186/s12872-021-02112-4