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Identification and functional characterization of a fish-specific tlr19 in common carp (Cyprinus carpio L.) that recruits TRIF as an adaptor and induces ifn expression during the immune response

Toll-like receptor 19 (Tlr19) is a fish-specific TLR that plays a critical role in innate immunity. In the present study, we aimed to identify tlr19 from common carp (Cyprinus carpio L.) and explored its expression profile, localization, adaptor, and signaling pathways. A novel tlr19 cDNA sequence (...

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Detalles Bibliográficos
Autores principales: Shan, Shijuan, Liu, Rongrong, Feng, Hanxiao, Meng, Fei, Aizaz, Muhanmmad, Yang, Guiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207781/
https://www.ncbi.nlm.nih.gov/pubmed/34130754
http://dx.doi.org/10.1186/s13567-021-00957-3