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A nadA Mutation Confers Nicotinic Acid Auxotrophy in Pro-carcinogenic Intestinal Escherichia coli NC101

Inflammatory bowel diseases (IBDs) and inflammation-associated colorectal cancer (CRC) are linked to blooms of adherent-invasive Escherichia coli (AIEC) in the intestinal microbiota. AIEC are functionally defined by their ability to adhere/invade epithelial cells and survive/replicate within macroph...

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Detalles Bibliográficos
Autores principales: Lopez, Lacey R., Barlogio, Cassandra J., Broberg, Christopher A., Wang, Jeremy, Arthur, Janelle C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207962/
https://www.ncbi.nlm.nih.gov/pubmed/34149655
http://dx.doi.org/10.3389/fmicb.2021.670005