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High Expression of Cancer-IgG Is Associated With Poor Prognosis and Radioresistance via PI3K/AKT/DNA-PKcs Pathway Regulation in Lung Adenocarcinoma

BACKGROUND: Lung adenocarcinoma (LUAD) is the dominant type of lung neoplasms, and radiotherapy is its mainstay treatment, yet poor prognosis caused by radioresistance remains problematic. Cancer-derived immunoglobulin G (cancer-IgG) has been detected in multiple cancers and plays important roles in...

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Detalles Bibliográficos
Autores principales: Yang, Xiongtao, Wang, Guohui, You, Jing, Gu, Runchuan, Xu, Xiaohong, Xu, Changdan, Wang, Hao, Zhao, Ruisong, Qiu, Xiaoyan, Zhu, Guangying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208032/
https://www.ncbi.nlm.nih.gov/pubmed/34150640
http://dx.doi.org/10.3389/fonc.2021.675397