Targeting novel human transient receptor potential ankyrin 1 splice variation with splice-switching antisense oligonucleotides

Activation of transient receptor potential ankyrin 1 (TRPA1) channels by both environmental irritants and endogenous inflammatory mediators leads to excitation of the nerve endings, resulting in acute sensation of pain, itch, or chronic neurogenic inflammation. As such, TRPA1 channels are actively p...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Hua, Tay, Shermaine Huiping, Ng, Winanto, Ng, Shi Yan, Soong, Tuck Wah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208096/
https://www.ncbi.nlm.nih.gov/pubmed/33938719
http://dx.doi.org/10.1097/j.pain.0000000000002216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208096/
https://www.ncbi.nlm.nih.gov/pubmed/33938719
http://dx.doi.org/10.1097/j.pain.0000000000002216

Ejemplares similares