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Targeting novel human transient receptor potential ankyrin 1 splice variation with splice-switching antisense oligonucleotides
Activation of transient receptor potential ankyrin 1 (TRPA1) channels by both environmental irritants and endogenous inflammatory mediators leads to excitation of the nerve endings, resulting in acute sensation of pain, itch, or chronic neurogenic inflammation. As such, TRPA1 channels are actively p...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wolters Kluwer
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208096/ https://www.ncbi.nlm.nih.gov/pubmed/33938719 http://dx.doi.org/10.1097/j.pain.0000000000002216 |