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Statistical optimization of bile salt deployed nanovesicles as a potential platform for oral delivery of piperine: accentuated antiviral and anti-inflammatory activity in MERS-CoV challenged mice

The objective of this paper is to confine piperine, a poor oral bioavailable herbal drug into bile salt based nano vesicles for improving its aqueous solubility, hence, its therapeutic activity. Piperine-loaded bilosomes were fabricated adopting thin film hydration technique according to 3(2).2(1) f...

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Detalles Bibliográficos
Autores principales: Zakaria, Mohamed Y., Fayad, Eman, Althobaiti, Fayez, Zaki, Islam, Abu Almaaty, Ali H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208124/
https://www.ncbi.nlm.nih.gov/pubmed/34121561
http://dx.doi.org/10.1080/10717544.2021.1934190