Competitive SPR using an intracellular anti-LMO2 antibody identifies novel LMO2-interacting compounds

The use of intracellular antibodies as templates to derive surrogate compounds is an important objective because intracellular antibodies can be employed initially for target validation in pre-clinical assays and subsequently employed in compound library screens. LMO2 is a T cell oncogenic protein a...

Descripción completa

Detalles Bibliográficos
Autores principales: Canning, Peter, Bataille, Carole, Bery, Nicolas, Milhas, Sabine, Hayes, Angela, Raynaud, Florence, Miller, Ami, Rabbitts, Terry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208243/
https://www.ncbi.nlm.nih.gov/pubmed/33794223
http://dx.doi.org/10.1016/j.jim.2021.113051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208243/
https://www.ncbi.nlm.nih.gov/pubmed/33794223
http://dx.doi.org/10.1016/j.jim.2021.113051

Ejemplares similares