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Competitive SPR using an intracellular anti-LMO2 antibody identifies novel LMO2-interacting compounds
The use of intracellular antibodies as templates to derive surrogate compounds is an important objective because intracellular antibodies can be employed initially for target validation in pre-clinical assays and subsequently employed in compound library screens. LMO2 is a T cell oncogenic protein a...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208243/ https://www.ncbi.nlm.nih.gov/pubmed/33794223 http://dx.doi.org/10.1016/j.jim.2021.113051 |