Palladium/Xu-Phos-catalyzed asymmetric carboamination towards isoxazolidines and pyrrolidines

An efficient palladium-catalyzed enantioselective carboamination reaction of N-Boc-O-homoallyl-hydroxylamines and N-Boc-pent-4-enylamines with aryl or alkenyl bromides was developed, delivering various substituted isoxazolidines and pyrrolidines in good yields with up to 97% ee. The reaction feature...

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Detalles Bibliográficos
Autores principales: Wang, Yuzhuo, Wang, Lei, Chen, Mingjie, Tu, Youshao, Liu, Yu, Zhang, Junliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208297/
https://www.ncbi.nlm.nih.gov/pubmed/34194715
http://dx.doi.org/10.1039/d1sc01337h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208297/
https://www.ncbi.nlm.nih.gov/pubmed/34194715
http://dx.doi.org/10.1039/d1sc01337h

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