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A minimal hybridization chain reaction (HCR) system using peptide nucleic acids

The HCR represents a powerful tool for amplification in DNA-based circuitry and sensing applications, yet requires the use of long DNA sequences to grant hairpin metastability. Here we describe a minimal HCR system based on peptide nucleic acids (PNAs). A system comprising a 5-mer stem and 5-mer loo...

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Detalles Bibliográficos
Autores principales: Kim, Ki Tae, Angerani, Simona, Winssinger, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208298/
https://www.ncbi.nlm.nih.gov/pubmed/34194712
http://dx.doi.org/10.1039/d1sc01269j