The Ras dimer structure

Oncogenic mutated Ras is a key player in cancer, but despite intense and expensive approaches its catalytic center seems undruggable. The Ras dimer interface is a possible alternative drug target. Dimerization at the membrane affects cell growth signal transduction. In vivo studies indicate that pre...

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Detalles Bibliográficos
Autores principales: Rudack, Till, Teuber, Christian, Scherlo, Marvin, Güldenhaupt, Jörn, Schartner, Jonas, Lübben, Mathias, Klare, Johann, Gerwert, Klaus, Kötting, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208300/
https://www.ncbi.nlm.nih.gov/pubmed/34194708
http://dx.doi.org/10.1039/d1sc00957e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208300/
https://www.ncbi.nlm.nih.gov/pubmed/34194708
http://dx.doi.org/10.1039/d1sc00957e

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