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Complement factor H protects tumor cell-derived exosomes from complement-dependent lysis and phagocytosis

Exosomes are a class of extracellular vesicles (EVs) that are mediators of normal intercellular communication, but exosomes are also used by tumor cells to promote oncogenesis and metastasis. Complement factor H (CFH) protects host cells from attack and destruction by the alternative pathway of comp...

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Detalles Bibliográficos
Autores principales: Bushey, Ryan T., Gottlin, Elizabeth B., Campa, Michael J., Patz, Edward F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208531/
https://www.ncbi.nlm.nih.gov/pubmed/34133431
http://dx.doi.org/10.1371/journal.pone.0252577