Clofarabine induces ERK/MSK/CREB activation through inhibiting CD99 on Ewing sarcoma cells

Clofarabine, an FDA approved purine analog, is used in the treatment of relapsed or refractory acute lymphoblastic leukemia. Clofarabine acts by inhibiting DNA synthesis. We demonstrated that clofarabine may have a novel function though inhibiting CD99, a transmembrane protein highly expressed on Ew...

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Detalles Bibliográficos
Autores principales: Sevim, Handan, Çelik, Haydar, Düşünceli, Levent, Ceyhan, Ceyda S., Molotkova, Anna, Nakazawa, Kay, Graham, Garrett T., Petro, Jeffrey R., Toretsky, Jeffrey A., Üren, Aykut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208565/
https://www.ncbi.nlm.nih.gov/pubmed/34133426
http://dx.doi.org/10.1371/journal.pone.0253170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208565/
https://www.ncbi.nlm.nih.gov/pubmed/34133426
http://dx.doi.org/10.1371/journal.pone.0253170

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