Extracellular proteolytic activation of Pseudomonas aeruginosa aminopeptidase (PaAP) and insight into the role of its non-catalytic N-terminal domain

Pseudomonas aeruginosa secretes several endopeptidases, including elastase, alkaline proteinase (Apr), a lysine-specific endopeptidase (LysC), and an aminopeptidase (PaAP), all of which are important virulence factors. Activation of the endopeptidases requires removal of an inhibitory N-terminal pro...

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Detalles Bibliográficos
Autores principales: Axelrad, Itschak, Safrin, Mary, Cahan, Rivka, Suh, Sang-Jin, Ohman, Dennis E., Kessler, Efrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208579/
https://www.ncbi.nlm.nih.gov/pubmed/34133429
http://dx.doi.org/10.1371/journal.pone.0252970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208579/
https://www.ncbi.nlm.nih.gov/pubmed/34133429
http://dx.doi.org/10.1371/journal.pone.0252970

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