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Extraction of rapid kinetics from smFRET measurements using integrative detectors
Hidden Markov models (HMMs) are used to learn single-molecule kinetics across a range of experimental techniques. By their construction, HMMs assume that single-molecule events occur on slower timescales than those of data acquisition. To move beyond that HMM limitation and allow for single-molecule...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208598/ https://www.ncbi.nlm.nih.gov/pubmed/34142102 http://dx.doi.org/10.1016/j.xcrp.2021.100409 |