Mechanisms underlying divergent responses of genetically distinct macrophages to IL-4

Mechanisms by which noncoding genetic variation influences gene expression remain only partially understood but are considered to be major determinants of phenotypic diversity and disease risk. Here, we evaluated effects of >50 million single-nucleotide polymorphisms and short insertions/deletion...

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Detalles Bibliográficos
Autores principales: Hoeksema, Marten A., Shen, Zeyang, Holtman, Inge R., Zheng, An, Spann, Nathan J., Cobo, Isidoro, Gymrek, Melissa, Glass, Christopher K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208725/
https://www.ncbi.nlm.nih.gov/pubmed/34134993
http://dx.doi.org/10.1126/sciadv.abf9808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208725/
https://www.ncbi.nlm.nih.gov/pubmed/34134993
http://dx.doi.org/10.1126/sciadv.abf9808

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