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Mechanisms underlying divergent responses of genetically distinct macrophages to IL-4
Mechanisms by which noncoding genetic variation influences gene expression remain only partially understood but are considered to be major determinants of phenotypic diversity and disease risk. Here, we evaluated effects of >50 million single-nucleotide polymorphisms and short insertions/deletion...
Autores principales: | Hoeksema, Marten A., Shen, Zeyang, Holtman, Inge R., Zheng, An, Spann, Nathan J., Cobo, Isidoro, Gymrek, Melissa, Glass, Christopher K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208725/ https://www.ncbi.nlm.nih.gov/pubmed/34134993 http://dx.doi.org/10.1126/sciadv.abf9808 |
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