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Neuronal loss and microgliosis are restricted to the core of Aβ deposits in mouse models of Alzheimer's disease

Amyloid‐β (Aβ) deposits, pathologic tau, and neurodegeneration are major pathological hallmarks of Alzheimer's disease (AD). The relationship between neuronal loss and Aβ deposits is one of the fundamental questions in the pathogenesis of AD. However, this relationship is controversial. One mai...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Wu, Na, Wang, Shubo, Yao, Zitong, Xiao, Fuchuan, Lu, Jing, Chen, Baian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208784/
https://www.ncbi.nlm.nih.gov/pubmed/34080759
http://dx.doi.org/10.1111/acel.13380