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Therapeutic efficacy of novel memantine nitrate MN‐08 in animal models of Alzheimer’s disease

Alzheimer's disease (AD) is a leading cause of dementia in elderly individuals and therapeutic options for AD are very limited. Over‐activation of N‐methyl‐D‐aspartate (NMDA) receptors, amyloid β (Aβ) aggregation, a decrease in cerebral blood flow (CBF), and downstream pathological events play...

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Detalles Bibliográficos
Autores principales: Wu, Liangmiao, Zhou, Xinhua, Cao, Yiwan, MAK, Shing Hung, Zha, Ling, Li, Ning, Su, Zhiyang, Han, Yifan, Wang, Yuqiang, Man Hoi, Maggie Pui, Sun, Yewei, Zhang, Gaoxiao, Zhang, Zaijun, Yang, Xifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208785/
https://www.ncbi.nlm.nih.gov/pubmed/33955647
http://dx.doi.org/10.1111/acel.13371