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Metabolipidomic profiling reveals an age‐related deficiency of skeletal muscle pro‐resolving mediators that contributes to maladaptive tissue remodeling

Specialized pro‐resolving mediators actively limit inflammation and support tissue regeneration, but their role in age‐related muscle dysfunction has not been explored. We profiled the mediator lipidome of aging muscle via liquid chromatography‐tandem mass spectrometry and tested whether treatment w...

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Detalles Bibliográficos
Autores principales: Markworth, James F., Brown, Lemuel A., Lim, Eunice, Castor‐Macias, Jesus A., Larouche, Jacqueline, Macpherson, Peter C. D., Davis, Carol, Aguilar, Carlos A., Maddipati, Krishna Rao, Brooks, Susan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208786/
https://www.ncbi.nlm.nih.gov/pubmed/34075679
http://dx.doi.org/10.1111/acel.13393