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Age‐related telomere attrition causes aberrant gene expression in sub‐telomeric regions

Telomere attrition has been proposed as a biomarker and causal factor in aging. In addition to causing cellular senescence and apoptosis, telomere shortening has been found to affect gene expression in subtelomeric regions. Here, we analyzed the distribution of age‐related differentially expressed g...

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Detalles Bibliográficos
Autores principales: Dong, Xiao, Sun, Shixiang, Zhang, Lei, Kim, Seungsoo, Tu, Zhidong, Montagna, Cristina, Maslov, Alexander Y., Suh, Yousin, Wang, Tao, Campisi, Judith, Vijg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208793/
https://www.ncbi.nlm.nih.gov/pubmed/34018656
http://dx.doi.org/10.1111/acel.13357