Copper-binding anticancer peptides from the piscidin family: an expanded mechanism that encompasses physical and chemical bilayer disruption

In the search for novel broad-spectrum therapeutics to fight chronic infections, inflammation, and cancer, host defense peptides (HDPs) have garnered increasing interest. Characterizing their biologically-active conformations and minimum motifs for function represents a requisite step to developing...

Descripción completa

Detalles Bibliográficos
Autores principales: Comert, Fatih, Heinrich, Frank, Chowdhury, Ananda, Schoeneck, Mason, Darling, Caitlin, Anderson, Kyle W., Libardo, M. Daben J., Angeles-Boza, Alfredo M., Silin, Vitalii, Cotten, Myriam L., Mihailescu, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208971/
https://www.ncbi.nlm.nih.gov/pubmed/34135370
http://dx.doi.org/10.1038/s41598-021-91670-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208971/
https://www.ncbi.nlm.nih.gov/pubmed/34135370
http://dx.doi.org/10.1038/s41598-021-91670-w

Ejemplares similares