Cancer-specific immune evasion and substantial heterogeneity within cancer types provide evidence for personalized immunotherapy

The immune response against cancer is orchestrated by various parameters and site-dependent specificities have been poorly investigated. In our analyses of ten different cancer types, we describe elevated infiltration by regulatory T cells as the most common feature, while other lymphocyte subsets a...

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Detalles Bibliográficos
Autores principales: Thelen, Martin, Wennhold, Kerstin, Lehmann, Jonas, Garcia-Marquez, Maria, Klein, Sebastian, Kochen, Elena, Lohneis, Philipp, Lechner, Axel, Wagener-Ryczek, Svenja, Plum, Patrick Sven, Velazquez Camacho, Oscar, Pfister, David, Dörr, Fabian, Heldwein, Matthias, Hekmat, Khosro, Beutner, Dirk, Klussmann, Jens Peter, Thangarajah, Fabinshy, Ratiu, Dominik, Malter, Wolfram, Merkelbach-Bruse, Sabine, Bruns, Christiane Josephine, Quaas, Alexander, von Bergwelt-Baildon, Michael, Schlößer, Hans A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208982/
https://www.ncbi.nlm.nih.gov/pubmed/34135436
http://dx.doi.org/10.1038/s41698-021-00196-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208982/
https://www.ncbi.nlm.nih.gov/pubmed/34135436
http://dx.doi.org/10.1038/s41698-021-00196-x

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