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Effects of topiramate on neural responses to alcohol cues in treatment-seeking individuals with alcohol use disorder: preliminary findings from a randomized, placebo-controlled trial

Topiramate, a GABA/glutamate modulator, is efficacious in reducing alcohol consumption, though the mechanisms underlying this effect are not well characterized. This study analyzed functional magnetic resonance imaging (fMRI) data from 22 heavy drinkers enrolled in a 12-week placebo-controlled, rand...

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Detalles Bibliográficos
Autores principales: Wetherill, Reagan R., Spilka, Nathaniel, Jagannathan, Kanchana, Morris, Paige, Romer, Danielle, Pond, Timothy, Lynch, Kevin G., Franklin, Teresa R., Kranzler, Henry R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208990/
https://www.ncbi.nlm.nih.gov/pubmed/33558678
http://dx.doi.org/10.1038/s41386-021-00968-w