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Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling

Ribosome biogenesis requires auxiliary factors to promote folding and assembly of ribosomal proteins and RNA. Particularly, maturation of the peptidyl transferase center (PTC) is mediated by conserved GTPases, but the molecular basis is poorly understood. Here, we define the mechanism of GTPase-driv...

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Detalles Bibliográficos
Autores principales: Hillen, Hauke S., Lavdovskaia, Elena, Nadler, Franziska, Hanitsch, Elisa, Linden, Andreas, Bohnsack, Katherine E., Urlaub, Henning, Richter-Dennerlein, Ricarda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209004/
https://www.ncbi.nlm.nih.gov/pubmed/34135319
http://dx.doi.org/10.1038/s41467-021-23702-y