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Osteocrin, a novel myokine, prevents diabetic cardiomyopathy via restoring proteasomal activity
Proteasomal activity is compromised in diabetic hearts that contributes to proteotoxic stresses and cardiac dysfunction. Osteocrin (OSTN) acts as a novel exercise-responsive myokine and is implicated in various cardiac diseases. Herein, we aim to investigate the role and underlying molecular basis o...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209005/ https://www.ncbi.nlm.nih.gov/pubmed/34135313 http://dx.doi.org/10.1038/s41419-021-03922-2 |