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Sensitive period for rescuing parvalbumin interneurons connectivity and social behavior deficits caused by TSC1 loss
The Mechanistic Target Of Rapamycin Complex 1 (mTORC1) pathway controls several aspects of neuronal development. Mutations in regulators of mTORC1, such as Tsc1 and Tsc2, lead to neurodevelopmental disorders associated with autism, intellectual disabilities and epilepsy. The correct development of i...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209106/ https://www.ncbi.nlm.nih.gov/pubmed/34135323 http://dx.doi.org/10.1038/s41467-021-23939-7 |