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PGC-1α mediates a metabolic host defense response in human airway epithelium during rhinovirus infections

Human rhinoviruses (HRV) are common cold viruses associated with exacerbations of lower airways diseases. Although viral induced epithelial damage mediates inflammation, the molecular mechanisms responsible for airway epithelial damage and dysfunction remain undefined. Using experimental HRV infecti...

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Detalles Bibliográficos
Autores principales: Michi, Aubrey N., Yipp, Bryan G., Dufour, Antoine, Lopes, Fernando, Proud, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209127/
https://www.ncbi.nlm.nih.gov/pubmed/34135327
http://dx.doi.org/10.1038/s41467-021-23925-z